Gene description for Hspa1a
Gene name heat shock protein family A (Hsp70) member 1A
Gene symbol Hspa1a
Other names/aliases HSP70-2
HSP70.1
HSP70.2
HSP72
Hsp70-1
Hspa1
Hspa1b
Species Rattus norvegicus
 Experiment description of studies that identified Hspa1a in Insulinoma cells

1
Experiment ID1220
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 27872147   
OrganismRattus norvegicus
Experiment descriptionPrimary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.
AuthorsCianciaruso C, Phelps EA, Pasquier M, Hamelin R, Demurtas D, Alibashe Ahmed M, Piemonti L, Hirosue S, Swartz MA, De Palma M, Hubbell JA, Baekkeskov S.
Journal name Diabetes.
Publication year2017
SampleInsulinoma cells
Sample nameINS-1E cells
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV160008: EV-METRIC:55%, 44%, 33%

2
Experiment ID1221
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 27872147   
OrganismRattus norvegicus
Experiment descriptionPrimary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.
AuthorsCianciaruso C, Phelps EA, Pasquier M, Hamelin R, Demurtas D, Alibashe Ahmed M, Piemonti L, Hirosue S, Swartz MA, De Palma M, Hubbell JA, Baekkeskov S.
Journal name Diabetes.
Publication year2017
SampleInsulinoma cells
Sample nameRat interleukin (IL)-1. (10 units/mL)
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV160008: EV-METRIC:55%, 44%, 33%

<